Newsletter

SOURCE 5 IS RELEASED!

SOURCE 5 is a stand-alone EEG Dipole Source Reconstruction. Program. SOURCE 5 uses functional (EEG, ECoG and MEG) and structural (MRI and CT) data to determine dipole source solutions. It provides several models that may be used to calculate one or more dipole solutions for averaged, epoched, or continuous functional data files. MRI and CT data can be used to identify electrode or grid positions and as a visual overlay of the solution space. Calculations are based on averaged realistic MRI models or spherical models.

Source 5 uses the Curry framework. It provides Basic tools for dipole source solutions in a simple, straight forward and cost effective package. There is flexibility without complexity and is ideal for learning and utilizing source reconstruction strategies in your lab.

Note: The functionality in Source 5 is a subset of that contained in Curry 6. For many users new to source reconstruction, Source 5 will provide all of the operations you need. For those users interested in more capabilities, for example, creating volume conductor models from the subject's MR data, using current density reconstruction models, and obtaining the most accurate source localization possible, Curry 6 may be more appropriate.

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Note: Source 5 runs as an independent program and does not require any other Neuroscan software.

For complete brochure contact Sales@neuroscan.com
Or visit our website at www.neuroscan.com

CURRY 6 RELEASE IS AT HAND!

German CURRY Team visits the USA to discuss the new features and plan release of CURRY 6 to the rest of the world.

Clockwise, left to right: Marty Ford, Jörn Kastner, Curtis Ponton, Ross Apparies, Bill Cameron, Michael Wagner,
Kathy Caplan, Anthony Curro, Manfred Fuchs and Rob Simon

“The new features make it much more powerful for multi-modality (combined MEG / EEG & anatomical images, mainly research) applications, but also 'standard' users will benefit from the redesigned User-Interface with toolbars for the most frequently used functions, the new montage editor, the wizard-supported Talairach co-ordinate system definition, automated co-registration of different image modalities and the other advanced features:” Manfred Fuchs, CURRY Team, Germany

NEW FEATURES OF CURRY 6
Multimodal source reconstructions from combined EEG and MEG data
EEG and MEG data can be combined after a Signal-to-Noise-transformation for increased information content and improved spatial resolution of source reconstructions. A conductivity factor can be fitted to take care of the not very well known in vivo conductivities that affect the EEG, but not the MEG solutions.

Additional functional data formats
Import filters for generic 4D-Neuroimaging (BTi), Neuroscan (*.fif), and XLTEK (Revision K) file formats

Montage editor
Allows to resort or remontage EEG measurements by specifying montages with a graphical User-Interface.

Template based event detection
The template based event detection can be used for epileptic spike detection / classification and averaging as well as for artifact detection followed by averaging and PCA-projection (see below).

PCA-projection for artifact suppression
Reduces eye blink or heart beat (ECG) artifacts by projecting the leading spatial-temporal components of the averaged artifact out of the data.

Time-resolved spectra (short time FFT)
Gives a color-coded overview of the frequency components that are contained in the data averaged over all channels. Time and frequency resolution are adjustable as well as linear and logarithmic color scales.

Vector beamformer scans
In addition to deviation and MUSIC scans, vector beamformer scans can be performed with and without given dipole orientations on the segmented cortical surface or on 3D-grids.

SWARM current density reconstructions (sLORETA-weighted minimum norm)
In contrast to sLORETA, SWARM results in currrent densities (similar to MNLS) instead of statistical measures for e.g. cortically constrained Current Density Reconstructions (CDRs).

Additional anatomical image data formats (DICOM)
An extension to the image data import wizard gives an overview of the different image data sets that can be contained in the series of DICOM images. Floating point data formats with offsets and lossless RLE- and JPEG-encoded images are supported.

Automated 3D-co-registration using mutual volume gray-level matching
Largely improved co-registration accuracy can be achieved by this parameter-free, automated procedure. After setting the principal landmarks (Nasion and Pre-Auricular Points) in the first image modality (normally MRI), the algorithm is able to automatically co-register e.g. CT and / or PET images to this 'master' image dataset by optimizing the alignment by statistically analyzing the gray-level of all image data voxels.

Talairach co-ordinates (wizard for bounding box definition)Wizard-guided specification of AC and PC (Anterior and Posterior Commissure) and the bounding box around the brain for Talairach base co-cordinate systems for normalized position and reconstruction result display.

Anatomical and functional atlases
Color-coded overlay and display of synonyms of different functional and anatomical atlases onto the structural image data.

Orthogonal cuts through segmented surfaces with volume image data display
3D-display of orthogonal cuts through segmented surfaces (skin or cortex) with overlay of definable image data sets.

Cortical inflation (smoothing)
Segmented surfaces (e.g. the cortex) can be inflated (smoothed) for simplified and improved visualization of cortical activity in sulci.

Full multi-core processor support (multi-threaded algorithms)
Largely improved computational performance for most of the time-consuming calculations by using parallelization.

OpenGL-accelerated 3D-graphics
Interactive real-time rendering of the whole 3D-scenario (skin, cortex, sensor geometry, and reconstruction results) on state-of -the-art graphics cards.

Highly interactive User-interface with toolbars for better accessibility of frequently used functions
Redesigned User-Interface with toolbars for the most frequently used functions.

Export of results to EXCEL, MATLAB, SPM
Results can be now be exported in these popular file formats.

Report generator (RTF-format)
Automated report-generation containing results in text-form and partial or full window screenshot graphics in the most versatile Rich Text Format, which can be processed by almost every text editor program.

CURRY 6 SCREENSHOTS

MEG and EEG: Medianus nerve stimulation, single moving dipole and cortically constrained deviation scan using a realistically shaped Boundary Element Method (BEM) volume conductor model:

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Co-registered anatomical 3D-datasets (MR, CT, and PET):
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Inflation (smoothing) of e.g. the cortical surface:

ECoG with cortically constrained current density reconstruction (MNLS, right hemisphere only), original and inflated surfaces with reconstruction results:
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NEUROSCAN WILL EXHIBIT AT THE FOLLOWING TRADE SHOWS

Oct 17-21	SPR- Society for Psycho physiological Research	Savannah, Georgia
Nov 3-7	SfN- Society for Neuroscience	San Diego, CA
Nov 30-Dec4	AES American Epilepsy Society	Philadelphia, A

NEUROSCAN EDUCATION/PRESENTATIONS:

CURRY and MAGLINK

Between 2005 and November 2006, Dr. John Ebersole discussed and demonstrated how advanced digital EEG analysis, source modeling, and in particular CURRY software, is employed in the evaluation of patients for epilepsy surgery at the University of Chicago. The Neuroscan CURRY Team was on hand to provide additional technical expertise and answer any questions.

Last year at the American Epilepsy Society, San Diego California Dr. Jersey Szaflarski presented: Recording EEG in the MRI environment: A presentation of case studies in Epilepsy. Dr. Szaflarski has significant experience with over 50 recordings providing more then 100 data sets collected with combined EEG and fMRI technology. He discussed how he uses this technology at the University of Cincinnati Medical Center for Imaging Research. Members of the Compumedics Neuroscan staff were once again on hand to provide additional expertise and answer questions...

Watch for information about Combined CURRY fMRI Symposium in Philadelphia December 2007

Regional and Full Scan Schools:
Regional SCAN School, Tempe Az. September 18-19, 2007
SCAN Course conducted by Rob Simon and Dr. Martin Ford PhD
Tuesday 9/18/07 Topics

Neuroscan system integration and overview
SCAN acquisition parameters I
SCAN acquisition parameters II
QuikCell Demo
Stim2 overview

Wednesday 9/19/07

SCAN analysis session I
SCAN analysis session II
Tcl Batch processing
Source reconstruction overview
General discussion of issues

Tuition: This 2-day course is $500.00

Location
Marriott Courtyard Tempe Downtown Hotel and Compumedics USA
601 South Ash Avenue
Tempe, AZ 85281
(480) 966-2800

Contact:
Kathy Caplan:
Tel. (216) 256-6629
Fax (216) 642-4241
e-mail: Kathy.caplan@compumedicsusa.com

Advanced SCAN and CURRY School
Irvine, California October 1-5, 2007
SCAN Course (M, T, W) Conducted by Dr. Curtis Ponton PhD

Electro-physiological Amplifiers
Electrodes and Transducers
SCAN Acquire
SCAN Batch Processing
SCAN analysis
Experimentations

CURRY (W, Th., F) Course Conducted by Dr. Michael Wagner PhD

Introduction to CURRY - History of Development
Analysis of Simulated Data
Hands-on Training
Analysis of Epileptic Spike Data
Anatomical Data Set Analysis: MR + CT

Tuition: Full week is $1600.00 The Advanced Scan and CURRY course can be divided into 3 days each. Wednesday October3 is an overlap day with Acquisition as demonstration

Location:
Marriott Courtyard Hotel and Compumedics USA
John Wayne Airport / Orange County
2701 Main Street,
Irvine California, 92614
(949) 757-1200

Contact:
Kathy Caplan:
Tel. (216) 256-6629
Fax (216) 642-4241
e-mail: Kathy.caplan@compumedicsusa.com

NEUROSCAN BASED PUBLICATIONS:

Development of Volume Conductor and Source Models to Localize Epileptic Focci.:
Journal of Clinical Neurophysiology 24(2):101-119, April 2007
Manfred Fuchs, Michael Wagner, Jörn Kastner
Generators of the intracranial P50 response in auditory sensory gating
NeuroImage 35(2):814-826, April 2007
Oleg Korzyukov, Mark E. Pflieger, Michael Wagner, Susan M. Bowyer, T. Rosburg, Karthik Sundaresan, Christian Erich Elger and Nashaat N. Boutros
From ECoG near fields to EEG and MEG far fields
New Frontiers in Biomagnetism, ICS 1300, Eds. D Cheyne, B Ross, G Stroink, H Weinberg, Elsevier, 2007, 125-128
Manfred Fuchs, Michael Wagner, Jörn Kastner
Compumedics Neuroscan is interested in your publications!
Have you recently published a paper using Compumedics Neuroscan systems or software?
We’d love the opportunity to post it on our website! Send your poster, abstract or link to Kathy.Caplan@compumedicsusa.com

SOURCE 5 IS RELEASED!

CURRY 6 RELEASE IS AT HAND!

German CURRY Team visits the USA to discuss the new features and plan release of CURRY 6 to the rest of the world. Clockwise, left to right: Marty Ford, Jörn Kastner, Curtis Ponton, Ross Apparies, Bill Cameron, Michael Wagner, Kathy Caplan, Anthony Curro, Manfred Fuchs and Rob Simon

CURRY 6 SCREENSHOTS

NEUROSCAN WILL EXHIBIT AT THE FOLLOWING TRADE SHOWS

NEUROSCAN EDUCATION/PRESENTATIONS:

German CURRY Team visits the USA to discuss the new features and plan release of CURRY 6 to the rest of the world.

Clockwise, left to right: Marty Ford, Jörn Kastner, Curtis Ponton, Ross Apparies, Bill Cameron, Michael Wagner,
Kathy Caplan, Anthony Curro, Manfred Fuchs and Rob Simon